Ineffectiveness of hyperbaric oxygen therapy in... (1986 study) Skip to main content
RCT Presse medicale (Paris, France : 1983) 1986

Ineffectiveness of hyperbaric oxygen therapy in multiple sclerosis. A randomized placebo-controlled double-blind study.

Confavreux C, Mathieu C, Chacornac R, Aimard G, Devic M, Presse medicale (Paris, France : 1983), 1986

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a double-blind, randomised, placebo-controlled trial involving 17 patients with definite and progressive multiple sclerosis to evaluate the effectiveness of hyperbaric oxygen therapy.

What They Found

The study found no significant benefit of hyperbaric oxygen therapy compared to placebo based on the Kurtzke disability status scale among the 17 patients. While a lesser proportion of patients receiving hyperbaric oxygen experienced deterioration of bowel/bladder function after 12 months, overall, the therapy was deemed ineffective for progressive multiple sclerosis.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

A significant limitation of this study is its small sample size of only 17 patients, which may limit the generalizability of the findings.

This plain-language summary was generated with AI assistance from the study's abstract; it has not been individually reviewed by a clinician. Always consult the source study and a qualified healthcare professional. See our editorial policy.

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Study Details

Study Type RCT
Category Neurological
Source Pubmed
PubMed ID 2950392
Year Published 1986
Journal Presse medicale (Paris, France : 1983)
MeSH Terms Double-Blind Method; Humans; Hyperbaric Oxygenation; Multiple Sclerosis; Random Allocation

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last updated: April 1, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology