Systematic Review The Journal of head trauma rehabilitation 2017

Is Hyperbaric Oxygen Therapy Effective for Traumatic Brain Injury? A Rapid Evidence Assessment of the Literature and Recommendations for the Field.

Crawford C, Teo L, Yang E, Isbister C, Berry K — The Journal of head trauma rehabilitation, 2017

View Original on PubMed PMID 27603765

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a systematic review of 12 randomised trials published through 2014 to assess the efficacy of hyperbaric oxygen therapy (HBO2) for traumatic brain injury (TBI).

What They Found

For mild TBI, studies showed no statistically significant difference between HBO2 and sham treatments, though both groups improved over time. For moderate-to-severe TBI, studies were of mixed quality, but the majority of results favored HBO2 compared to standard care.

Canadian Relevance

This systematic review did not include any specific Canadian data or studies.

Study Limitations

Limitations included mixed methodological quality and flawed designs in some moderate-to-severe TBI studies, and a lack of detail in placebo analyses.

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Study Details

Study Type	Systematic Review
Category	Neurological
Source	Pubmed
PubMed ID	27603765
Year Published	2017
Journal	The Journal of head trauma rehabilitation
MeSH Terms	Brain Concussion; Evidence-Based Medicine; Female; Humans; Hyperbaric Oxygenation; Male; Practice Guidelines as Topic; Prognosis; Randomized Controlled Trials as Topic; Treatment Outcome

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology