Lidocaine in the treatment of decompression illness: a review of the literature. | Canada Hyperbarics Skip to main content
RCT Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc 2001

Lidocaine in the treatment of decompression illness: a review of the literature.

Mitchell SJ — Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 2001

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a review of the literature on lidocaine's use in treating decompression illness.

What They Found

The review found that lidocaine is neuroprotective in cerebral arterial gas embolism (CAGE) and various models of ischemic brain injury. One randomized double-blind study showed improved neuropsychological outcomes in cardiac surgery patients receiving lidocaine, though clinical evidence for decompression illness (DCI) is limited to anecdotal reports.

What This Means for Canadian Patients

Canadian patients experiencing unequivocal cerebral arterial gas embolism (CAGE) may benefit from expeditious lidocaine administration. For severe neurologic decompression illness (DCI), its speculative use might be considered after thorough patient counseling and consent.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

The clinical evidence for lidocaine's efficacy in decompression illness is primarily limited to anecdotal reports and limited in vivo investigation.

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Study Details

Study Type RCT
Category Neurological
Source Pubmed
PubMed ID 12067153
Year Published 2001
Journal Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
MeSH Terms Cell Hypoxia; Decompression Sickness; Energy Metabolism; Humans; Intracranial Embolism; Lidocaine; Neurons; Neuroprotective Agents

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.