Clinical Study Computational intelligence and neuroscience 2022

Magnetic Resonance Imaging to Evaluate the Recovery Effects of Cerebral Nerve Function in Comprehensive Treatment of Poststroke Depression by Intelligent Algorithm-Based Hyperbaric Oxygen Therapy.

Yuan C, Zhang L, Hao Y, Liang J, Ma T — Computational intelligence and neuroscience, 2022

View Original on PubMed PMID 35401732

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated the effects of hyperbaric oxygen therapy combined with escitalopram oxalate on poststroke depression by comparing 118 patients randomised to receive either the combined therapy or escitalopram oxalate alone.

What They Found

Patients receiving hyperbaric oxygen therapy in addition to escitalopram oxalate showed lower National Institutes of Health Stroke Scale (NIHSS) and Hamilton Depression Scale (HAMD) scores after treatment compared to the control group. The research group also exhibited a glial fibrillary acidic protein (GFAP) level of 852.46 ± 94.47, suggesting changes in neurological markers.

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada, nor did it involve Canadian researchers or participants.

Study Limitations

The study's generalizability may be limited by its specific patient population and the abstract's incomplete reporting of all outcome measures.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Clinical Study
Category	Neurological
Source	Pubmed
PubMed ID	35401732
Year Published	2022
Journal	Computational intelligence and neuroscience
MeSH Terms	Algorithms; Depression; Humans; Hyperbaric Oxygenation; Intelligence; Magnetic Resonance Imaging

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Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology