Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis. | Canada Hyperbarics Skip to main content
Meta-Analysis Lancet (London, England) 2018 Canadian

Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis.

Chu DK, Kim LH, Young PJ, Zamiri N, Almenawer SA, Jaeschke R, et al. — Lancet (London, England), 2018

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a systematic review and meta-analysis to evaluate the efficacy and safety of liberal versus conservative oxygen therapy in acutely ill adults.

What They Found

The abstract describes the methodology for assessing main outcomes, including mortality (in-hospital, 30-day, and longest follow-up) and morbidity (disability, hospital-acquired pneumonia, any hospital-acquired infection, and length of hospital stay). However, the provided abstract does not present the specific numerical findings or conclusions from the meta-analysis.

What This Means for Canadian Patients

Understanding the optimal oxygen therapy strategy could improve outcomes for acutely ill Canadian patients by informing clinical practice. This research aims to guide healthcare providers in delivering safer and more effective care in Canadian hospitals.

Canadian Relevance

This systematic review and meta-analysis, co-authored by Canadian researchers, synthesizes global evidence on oxygen therapy. The findings are directly relevant to informing clinical practice and guidelines for acutely ill patients across Canada.

Study Limitations

Potential limitations of such a meta-analysis include the heterogeneity of included trials and the quality of the primary studies synthesized.

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Study Details

Study Type Meta-Analysis
Category Neurological
Source Pubmed
PubMed ID 29726345
Year Published 2018
Journal Lancet (London, England)
MeSH Terms Adult; Aged; Aged, 80 and over; Conservative Treatment; Critical Illness; Cross Infection; Female; Hospital Mortality; Humans; Iatrogenic Disease; Length of Stay; Male; Middle Aged; Morbidity; Myocardial Infarction

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.