Neuromodulation on cervical spinal cord combined with hyperbaric oxygen in comatose patients--a preliminary report. | Canada Hyperbarics Skip to main content
Prospective Study Surgical neurology 2009

Neuromodulation on cervical spinal cord combined with hyperbaric oxygen in comatose patients--a preliminary report.

Liu JT, Lee JK, Tyan YS, Liu CY, Chen YH, Lin TB — Surgical neurology, 2009

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a prospective trial to evaluate the combined effect of cervical spinal cord stimulation (cSCS) and hyperbaric oxygen (HBO) therapy in 12 comatose patients, comparing them to a control group of 12 patients receiving median nerve stimulation only.

What They Found

Six of the 12 patients (50%) who received combined cSCS and HBO therapy emerged from coma at 1 year, showing significant increases in Glasgow Coma Scale score, SPECT imaging, and PVS scores (P < .05) compared to enrollment. In contrast, the control group showed no apparent improvement.

What This Means for Canadian Patients

This preliminary study suggests that a combination of cervical spinal cord stimulation and hyperbaric oxygen therapy could potentially improve outcomes for some comatose patients. However, further robust research is required before these findings could be considered for widespread clinical application in Canada.

Canadian Relevance

There is no direct Canadian connection mentioned in this study.

Study Limitations

This was a preliminary report with a small sample size and lacked randomization, limiting the generalizability of its findings.

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Study Details

Study Type Prospective Study
Category Neurological
Source Pubmed
PubMed ID 19665182
Year Published 2009
Journal Surgical neurology
MeSH Terms Adult; Biomarkers; Brain Hemorrhage, Traumatic; Cerebrovascular Circulation; Cervical Vertebrae; Coma; Combined Modality Therapy; Electric Stimulation Therapy; Electrodes, Implanted; Enteral Nutrition; Female; Glasgow Coma Scale; Humans; Hyperbaric Oxygenation; Male

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.