Neuromodulation on cervical spinal cord combined with hyperbaric oxygen in comatose patients--a preliminary report. | Canada Hyperbarics Skip to main content
Prospective Study Surgical neurology 2009

Neuromodulation on cervical spinal cord combined with hyperbaric oxygen in comatose patients--a preliminary report.

Liu JT, Lee JK, Tyan YS, Liu CY, Chen YH, Lin TB — Surgical neurology, 2009

View Original on PubMed PMID 19665182
Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a prospective trial to evaluate the combined effect of cervical spinal cord stimulation (cSCS) and hyperbaric oxygen (HBO) therapy in 12 comatose patients, comparing them to a control group of 12 patients receiving median nerve stimulation only.

What They Found

Six of the 12 patients (50%) who received combined cSCS and HBO therapy emerged from coma at 1 year, showing significant increases in Glasgow Coma Scale score, SPECT imaging, and PVS scores (P < .05) compared to enrollment. In contrast, the control group showed no apparent improvement.

Canadian Relevance

There is no direct Canadian connection mentioned in this study.

Study Limitations

This was a preliminary report with a small sample size and lacked randomization, limiting the generalizability of its findings.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Prospective Study
Category Neurological
Source Pubmed
PubMed ID 19665182
Year Published 2009
Journal Surgical neurology
MeSH Terms Adult; Biomarkers; Brain Hemorrhage, Traumatic; Cerebrovascular Circulation; Cervical Vertebrae; Coma; Combined Modality Therapy; Electric Stimulation Therapy; Electrodes, Implanted; Enteral Nutrition; Female; Glasgow Coma Scale; Humans; Hyperbaric Oxygenation; Male

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Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology