Study Neural Regen Res 2016

Neuroprotection of hyperbaric oxygen therapy in sub-acute traumatic brain injury: not by immediately improving cerebral oxygen saturation and oxygen partial pressure

Zhou B, Liu L, Liu B — Neural Regen Res, 2016

View Original on PubMed PMID 27857747

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers compared 40 patients with sub-acute traumatic brain injury (TBI) who received hyperbaric oxygen therapy (HBOT) to 20 healthy individuals to understand how HBOT affects brain oxygen levels.

What They Found

The 40 TBI patients received 100% oxygen HBOT for 90 minutes. After treatment, their brain oxygen saturation (rSO2) levels did not change significantly, and remained lower than those of healthy controls. Additionally, oxygen partial pressure (PaO2) levels significantly decreased after 30 minutes of HBOT.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

The study's main limitation is that it only examined the immediate effects of HBOT on cerebral oxygen metabolism, and the underlying mechanisms for TBI recovery still require further investigation.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

Was this summary helpful?

Study Details

Study Type	Study
Category	Neurological
Source	Pubmed
PubMed ID	27857747
Year Published	2016
Journal	Neural Regen Res

Related Research

PLoS ONE | 2013 RCT

Hyperbaric oxygen induces late neuroplasticity in post stroke patients--randomized, prospective trial.

Efrati S, Fishlev G, Bechor Y, et al.

J Neurotrauma | 2018 Systematic Review

Hyperbaric oxygen therapy in the treatment of acute severe traumatic brain injury: a systematic review

Daly S, Thorpe M, Rockswold S, et al.

J Neurotrauma | 2012 Pilot Study

A phase I study of low-pressure hyperbaric oxygen therapy for blast-induced post-concussion syndrome and PTSD

Harch PG, Andrews SR, Fogarty EF, et al.

Scientific Reports | 2022 RCT

Hyperbaric oxygen therapy improves neurocognitive functions and symptoms of post-COVID condition: randomized controlled trial.

Hadanny A, Zilberman-Itskovich S, Catalogna M, et al.

PLoS ONE | 2013 RCT

Hyperbaric oxygen therapy can improve post concussion syndrome years after mild traumatic brain injury — randomized prospective trial

Boussi-Gross R, Golan H, Fishlev G, et al.

See all Neurological research

View on PubMed Back to Research Library

Discuss with a qualified healthcare professional. Then: Review Coverage Guide View Recognised Conditions

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 17, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology