RCT Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc 2016

Neuropsychological assessments in a hyperbaric trial of post-concussive symptoms.

Wilson SH, Weaver LK, Lindblad AS — Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 2016

View Original on PubMed PMID 28768075

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers compared neuropsychological assessments between U.S. military service members with mild traumatic brain injury (mTBI) only (n=36) and those with mTBI plus post-traumatic stress disorder (PTSD) (n=35) from a randomised interventional study.

What They Found

The mTBI group reported worse symptoms than published norms, with over 50% showing abnormal scores on PCS, PTSD, and pain scales. The mTBI+PTSD group exhibited significantly worse symptom reporting (mean NSI total score 39.9 vs. 27.5, p<0.001) and performed worse on cognitive tasks like digit span (mean difference -1.5, p=0.04) and Grooved Pegboard (dominant hand mean difference -7.0, p=0.003) compared to the mTBI-only group.

Canadian Relevance

This study was conducted with U.S. military service members and does not have a direct Canadian connection.

Study Limitations

The findings are based on a specific population of U.S. military personnel, which may limit their generalizability to broader patient populations.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	RCT
Category	Neurological
Source	Pubmed
PubMed ID	28768075
Year Published	2016
Journal	Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
MeSH Terms	Adult; Brain Concussion; Depression; Female; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Military Personnel; Neuropsychological Tests; Post-Concussion Syndrome; Quality of Life; Randomized Controlled Trials as Topic; Stress Disorders, Post-Traumatic; Surveys and Questionnaires

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Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology