Retrospective Study Neurological research 2003

Optimal dosing as a necessary condition for the efficacy of hyperbaric oxygen therapy in acute ischemic stroke: a critical review.

Rogatsky GG, Shifrin EG, Mayevsky A — Neurological research, 2003

View Original on PubMed PMID 12564134

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers retrospectively analyzed published clinical studies involving 265 patients to determine the relationship between hyperbaric oxygen therapy (HBOT) dose and efficacy in acute ischaemic stroke.

What They Found

They found a strong correlation (r = 0.92) between increasing HBOT dose and higher efficacy in improving neurological status. The maximum possible efficacy of 100% was observed when the average total HBOT dose reached at least 30 agreed units.

Canadian Relevance

There is no direct Canadian connection mentioned in this retrospective review.

Study Limitations

A key limitation is the retrospective nature of the analysis, which relies on previously published data from various hyperbaric centers.

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Study Details

Study Type	Retrospective Study
Category	Neurological
Source	Pubmed
PubMed ID	12564134
Year Published	2003
Journal	Neurological research
MeSH Terms	Brain Ischemia; Dose-Response Relationship, Drug; Humans; Hyperbaric Oxygenation; Retrospective Studies; Treatment Outcome

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology