Clinical Study Investigative ophthalmology & visual science 1980

Oxygen lowers intraocular pressure.

Gallin-Cohen PF, Podos SM, Yablonski ME — Investigative ophthalmology & visual science, 1980

View Original on PubMed PMID 7350133

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated the effect of increased atmospheric pressure and 100% oxygen administration on intraocular pressure in 14 human patients and 20 rabbits.

What They Found

They found a significant decrease in intraocular pressure in 14 patients when atmospheric pressure was increased and also when 100% oxygen was administered. A significant decrease in intraocular pressure also occurred in 20 rabbits receiving 100% oxygen, with results in human oxygen and hyperbaric groups being statistically similar.

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada nor involved Canadian researchers or participants.

Study Limitations

The study's limitations include a small sample size of 14 human patients and the use of an animal model, which may limit generalizability.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

Was this summary helpful?

Study Details

Study Type	Clinical Study
Category	Ocular / Retinal
Source	Pubmed
PubMed ID	7350133
Year Published	1980
Journal	Investigative ophthalmology & visual science
MeSH Terms	Animals; Humans; Hyperbaric Oxygenation; Intraocular Pressure; Oxygen; Oxygen Inhalation Therapy; Rabbits

Related Research

Undersea Hyperb Med | 2018 Clinical Study

Effect of hyperbaric oxygen treatment in central retinal artery occlusion

Bagli BS, Cevik SG, Cevik MT.

Clin Ophthalmol | 2021 Clinical Guideline

Hyperbaric oxygen therapy for central retinal artery occlusion: patient selection and perspectives

Celebi ARC, Kiener H.

Korean J Ophthalmol | 2022 Meta-Analysis

The Effects of Hyperbaric Oxygen Therapy in Patients with Central Retinal Artery Occlusion: A Retrospective Study, Systematic Review, and Meta-analysis

Rosignoli L, Chu E, Carter J, Johnson D, Sohn J, Bahadorani S

J Clin Med | 2026 Meta-Analysis

Hyperbaric Oxygen Therapy Versus Intravenous Thrombolysis in the Treatment of Central Retinal Artery Occlusion: A Systematic Review and Meta-Analysis

Bakdalieh A, Siddiqui D, Chen D, Yu M

Minerva Anestesiol | 2001 RCT

Lipid peroxidation, circulating cytokine and endothelin 1 levels in healthy volunteers undergoing hyperbaric oxygenation

Rocco M, Antonelli M, Letizia V, Alampi D, Spadetta G, Passariello M, et al.

See all Ocular / Retinal research

View on PubMed Back to Research Library

Find a Canadian Clinic Treating Ocular / Retinal

Browse verified hyperbaric facilities across Canada.

View Canadian Facilities

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology