What Researchers Did
Researchers compiled and summarized findings from 145 peer-reviewed articles about patent foramen ovale (PFO) and its link to paradoxical systemic embolism.
What They Found
The review found that patent foramen ovale (PFO) is considered an important risk factor for stroke due to paradoxical systemic embolization. It also identified PFO as a potential pathway for venous gas bubbles, formed after decompression, to enter the arterial system. The authors noted an ongoing debate about screening aviators, astronauts, and scuba divers for PFO.
Canadian Relevance
This study covers decompression sickness, a Health Canada-recognised indication for hyperbaric oxygen therapy. No direct Canadian authors or study sites were identified.
Study Limitations
As a bibliographic review, this study synthesizes existing literature rather than presenting new primary research findings or patient data.