Clinical Study Annals of emergency medicine 1983

Phenytoin sodium in oxygen-toxicity-induced seizures.

Weaver LK — Annals of emergency medicine, 1983

View Original on PubMed PMID 6849525

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers presented a case study of a patient with cerebral air embolism complicated by oxygen-induced seizures, who was treated with phenytoin sodium during hyperbaric recompression.

What They Found

In this single case, phenytoin sodium appeared to inhibit seizure activity in a patient experiencing oxygen-induced seizures in a hyperbaric environment. This inhibition subsequently allowed the patient to continue treatment with hyperbaric oxygen.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

A significant limitation of this study is its single-case report design, which prevents generalization of findings.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

Was this summary helpful?

Study Details

Study Type	Clinical Study
Category	Neurological
Source	Pubmed
PubMed ID	6849525
Year Published	1983
Journal	Annals of emergency medicine
MeSH Terms	Adult; Diving; Embolism, Air; Humans; Hyperbaric Oxygenation; Intracranial Embolism and Thrombosis; Male; Phenytoin; Seizures

Related Research

PLoS ONE | 2013 RCT

Hyperbaric oxygen induces late neuroplasticity in post stroke patients--randomized, prospective trial.

Efrati S, Fishlev G, Bechor Y, et al.

J Neurotrauma | 2018 Systematic Review

Hyperbaric oxygen therapy in the treatment of acute severe traumatic brain injury: a systematic review

Daly S, Thorpe M, Rockswold S, et al.

J Neurotrauma | 2012 Pilot Study

A phase I study of low-pressure hyperbaric oxygen therapy for blast-induced post-concussion syndrome and PTSD

Harch PG, Andrews SR, Fogarty EF, et al.

Scientific Reports | 2022 RCT

Hyperbaric oxygen therapy improves neurocognitive functions and symptoms of post-COVID condition: randomized controlled trial.

Hadanny A, Zilberman-Itskovich S, Catalogna M, et al.

PLoS ONE | 2013 RCT

Hyperbaric oxygen therapy can improve post concussion syndrome years after mild traumatic brain injury — randomized prospective trial

Boussi-Gross R, Golan H, Fishlev G, et al.

See all Neurological research

View on PubMed Back to Research Library

Discuss with a qualified healthcare professional. Then: Review Coverage Guide View Recognised Conditions

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology