RCT Neurorehabilitation and neural repair 2014

Randomized, Sham-Controlled, Feasibility Trial of Hyperbaric Oxygen for Service Members With Postconcussion Syndrome: Cognitive and Psychomotor Outcomes 1 Week Postintervention.

Walker WC, Franke LM, Cifu DX, Hart BB — Neurorehabilitation and neural repair, 2014

View Original on PubMed PMID 24370568

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a randomised, double-blind, sham-controlled feasibility trial involving 60 male active-duty marines with postconcussion syndrome to evaluate the effects of hyperbaric oxygen on psychomotor and cognitive performance.

What They Found

The study found no significant differences in psychomotor (balance and fine motor) or cognitive performance among the three groups (Sham Air, 1.5 ATAO2, 2.0 ATAO2) one week after 40 hyperbaric oxygen sessions. Despite analyzing multiple sensitive cognitive and psychomotor measures in 60 participants, no significant improvements were observed in any of the tested outcomes.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

A limitation is that this was a feasibility trial, potentially not powered for efficacy, and the study population was specific to male active-duty marines.

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Study Details

Study Type	RCT
Category	Neurological
Source	Pubmed
PubMed ID	24370568
Year Published	2014
Journal	Neurorehabilitation and neural repair
MeSH Terms	Adult; Attention; Brain Concussion; Cognition; Double-Blind Method; Executive Function; Feasibility Studies; Humans; Hyperbaric Oxygenation; Male; Memory, Short-Term; Military Personnel; Neuropsychological Tests; Post-Concussion Syndrome; Postural Balance

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology