Clinical Study Anesthesia and analgesia 1997

Recommendations for hyperbaric oxygen therapy of cerebral air embolism based on a mathematical model of bubble absorption.

Dexter F, Hindman BJ — Anesthesia and analgesia, 1997

View Original on PubMed PMID 9174293

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers used a mathematical model to predict the absorption time of cerebral artery air emboli (CAAE) of varying volumes.

What They Found

The model predicted that cerebral artery air emboli (CAAE) would take at least 40 hours to absorb with 40% inspired oxygen. For CAAE large enough to be detected by CT, absorption times were calculated to be at least 15 hours. The study suggests considering hyperbaric oxygen therapy if large CAAE are visualized on CT, even with transfer delays.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

The findings are based on a mathematical model rather than direct clinical observation or patient data.

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Study Details

Study Type	Clinical Study
Category	Neurological
Source	Pubmed
PubMed ID	9174293
Year Published	1997
Journal	Anesthesia and analgesia
MeSH Terms	Absorption; Cerebral Arterial Diseases; Embolism, Air; Humans; Hyperbaric Oxygenation; Mathematical Computing; Models, Biological; Nitrogen; Partial Pressure

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology