Rejuvenation Through Oxygen, More or Less. (2021 study) Skip to main content
Clinical Study Rejuvenation research 2021

Rejuvenation Through Oxygen, More or Less.

Kamat SM, Mendelsohn AR, Larrick JW, Rejuvenation research, 2021

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reviewed how changing oxygen levels in the body, including hyperbaric oxygen therapy, might affect signs of aging in older adults.

What They Found

This review describes two earlier small studies: one clinical trial gave older adults 60 sessions of hyperbaric oxygen therapy and found longer average telomere length (a marker of cell aging) in several types of immune cells, including B cells, natural killer cells, and helper and cytotoxic T lymphocytes. The same trial also found fewer CD28null senescent (aged) helper and cytotoxic T cells, meaning a reduction in this marker of immune cell aging. A separate report found that hyperbaric oxygen therapy was associated with better attention and information processing speed in older adults, linked to increased blood flow in brain regions where blood flow tends to decline with age. The abstract states that how long these changes last is not yet known.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This is a review discussing results from other small trials rather than new original research, and the abstract notes the durability of the changes is undetermined and further characterization is required.

This plain-language summary was generated with AI assistance from the study's abstract; it has not been individually reviewed by a clinician. Always consult the source study and a qualified healthcare professional. See our editorial policy.

Was this summary helpful?

Study Details

Study Type Clinical Study
Category Aging & Longevity
Source Pubmed
PubMed ID 33784834
Year Published 2021
Journal Rejuvenation research
MeSH Terms Aged; Animals; Cognition; Humans; Hyperoxia; Hypoxia; Oxygen; Rejuvenation

Cite This Study

Share

Find a Canadian Clinic

Browse verified hyperbaric facilities across Canada.

View Canadian Facilities

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last updated: April 1, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology