Case Study Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc 2020

Successful adjunctive treatment of compartment syndrome due to acute isocyanate inhalation using hyperbaric oxygen therapy: case report.

Lee S, Han J, Heo T — Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 2020

View Original on PubMed PMID 32931672

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported on a 58-year-old man who developed compartment syndrome and rhabdomyolysis after acute isocyanate inhalation and was successfully treated with hyperbaric oxygen therapy following fasciotomy.

What They Found

A 58-year-old man exposed to isocyanate developed compartment syndrome with creatine kinase levels of 15,250 IU/L and lower leg tissue pressures of 180/170 mmHg. Following fasciotomy and seven days of hyperbaric oxygen therapy (2.0 ATA for 90 minutes twice daily), his condition improved over five months, preventing amputation.

Canadian Relevance

This case report has no direct Canadian connection.

Study Limitations

As a single case report, the findings cannot be generalized to a broader patient population.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Case Study
Category	Neurological
Source	Pubmed
PubMed ID	32931672
Year Published	2020
Journal	Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
MeSH Terms	Anterior Compartment Syndrome; Combined Modality Therapy; Compartment Syndromes; Creatine Kinase; Fasciotomy; Humans; Hyperbaric Oxygenation; Isocyanates; Male; Middle Aged; Rhabdomyolysis; Time Factors; Treatment Outcome

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Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology