T helper 1 response is correlated with widespread pain, fatigue, sleeping disorders and the quality of life in patients with fibromyalgia and is modulated by hyperbaric oxygen therapy. | Canada Hyperbarics Skip to main content
Clinical Study Clinical and experimental rheumatology 2019

T helper 1 response is correlated with widespread pain, fatigue, sleeping disorders and the quality of life in patients with fibromyalgia and is modulated by hyperbaric oxygen therapy.

Guggino G, Schinocca C, Lo Pizzo M, Di Liberto D, Garbo D, Raimondo S, et al. — Clinical and experimental rheumatology, 2019

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated the effect of hyperbaric oxygen therapy (HBOT) on the immune system and quality of life in patients with fibromyalgia (FM) compared to controls.

What They Found

Fibromyalgia patients exhibited a T helper 1 (Th1) immune signature, which correlated with widespread pain, fatigue, sleeping disorders, and reduced quality of life. Hyperbaric oxygen therapy modulated this Th1 activation and impacted proinflammatory cytokine production by CD4 T cells. This modulation was associated with improvements in patient symptoms and quality of life.

What This Means for Canadian Patients

This study suggests that hyperbaric oxygen therapy could be a beneficial treatment option for Canadian patients with fibromyalgia, potentially alleviating symptoms like pain, fatigue, and sleep disturbances. By modulating the immune system, HBOT may offer a new approach to improve the quality of life for those living with this chronic condition.

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada nor involved Canadian participants or researchers.

Study Limitations

The study's generalizability may be limited by its specific patient cohort and the absence of long-term follow-up data.

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Study Details

Study Type Clinical Study
Category Neurological
Source Pubmed
PubMed ID 30747094
Year Published 2019
Journal Clinical and experimental rheumatology
MeSH Terms CD4 Lymphocyte Count; Cytokines; Fatigue; Fibromyalgia; Humans; Hyperbaric Oxygenation; Quality of Life; Sleep; Th1 Cells

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.