Retrospective Study Int J Neurosci 2025

The effects of hyperbaric oxygen therapy on neuroprotection and recovery after brain resuscitation

Li D, He X, Li Y, Wu S, Liu J — Int J Neurosci, 2025

View Original on PubMed PMID 38646692

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reviewed records from 83 patients with severe traumatic brain injury to compare standard treatment against standard treatment plus HBOT.

What They Found

The HBOT group had an 80.95% overall treatment effectiveness rate compared to 60.98% in the control group. Brain injury biomarkers (S100β, NSE, GFAP) were significantly lower in HBOT patients, while brain growth factors (NGF and BDNF) were significantly higher. Neurological function scores also improved more in the HBOT group, with no added risk of side effects.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This was a retrospective study at a single institution in China, and the relatively small sample size of 83 patients limits how broadly the findings can be applied.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Retrospective Study
Category	Neurological
Source	Pubmed
PubMed ID	38646692
Year Published	2025
Journal	Int J Neurosci
MeSH Terms	Humans; Hyperbaric Oxygenation; Male; Female; Adult; Middle Aged; Retrospective Studies; Neuroprotection; Brain Injuries, Traumatic; Recovery of Function; Brain-Derived Neurotrophic Factor; Resuscitation; Nerve Growth Factor; Nerve Growth Factors; Aged; Young Adult

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology