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Review Journal of cellular physiology 2021

The effects of hyperbaric oxygen therapy on the brain with middle cerebral artery occlusion.

Thiankhaw K, Chattipakorn N, Chattipakorn SC — Journal of cellular physiology, 2021

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a review of existing in vivo and clinical data to evaluate the potential benefits and effectiveness of hyperbaric oxygen therapy (HBOT) for middle cerebral artery occlusion (MCAO) and cerebral ischemia/reperfusion injury.

What They Found

The review found evidence from animal and clinical studies suggesting positive effects of hyperbaric oxygen therapy (HBOT) on neurological outcomes following cerebral ischemia. However, the review also highlighted conflicting evidence, with some studies indicating that HBOT may not improve functional recovery after ischemic injury.

What This Means for Canadian Patients

For Canadian patients experiencing ischemic stroke due to middle cerebral artery occlusion, hyperbaric oxygen therapy (HBOT) is an area of ongoing research with mixed evidence regarding its benefits. Patients should discuss all treatment options with their healthcare providers, as current evidence does not definitively support HBOT as a standard treatment for improving functional recovery after stroke.

Canadian Relevance

This review does not have a direct Canadian connection.

Study Limitations

A limitation of the current evidence base, as highlighted by this review, is the conflicting data regarding the effectiveness of hyperbaric oxygen therapy on functional recovery after ischemic injury.

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Study Details

Study Type Review
Category Neurological
Source Pubmed
PubMed ID 32692455
Year Published 2021
Journal Journal of cellular physiology
MeSH Terms Animals; Brain; Humans; Hyperbaric Oxygenation; Infarction, Middle Cerebral Artery; Inflammation; Oxidative Stress; Stroke

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.