The National Brain Injury Rescue and Rehabilitation Study - a multicenter observational study of hyperbaric oxygen for mild traumatic brain injury with post-concussive symptoms | Canada Hyperbarics Skip to main content
Study Med Gas Res 2019

The National Brain Injury Rescue and Rehabilitation Study - a multicenter observational study of hyperbaric oxygen for mild traumatic brain injury with post-concussive symptoms

Mozayeni B, Duncan W, Zant E, Love T, Beckman R, Stoller K — Med Gas Res, 2019

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a multicenter observational study testing the safety and feasibility of HBOT (40 to 82 sessions at 1.5 ATA for one hour each) in 32 patients with chronic post-concussive symptoms from mild traumatic brain injury, measuring neurocognitive outcomes.

What They Found

Subjects showed improvement in 21 of 25 neurocognitive test measures. Objective cognitive test components improved in 13 of 17 measures. Earlier treatment after injury, younger age, military status, and more HBOT sessions were all associated with better outcomes. No adverse events were reported.

What This Means for Canadian Patients

Mild TBI and post-concussion syndrome affect Canadian athletes, veterans, and motor vehicle accident victims. This study adds to accumulating evidence that HBOT can meaningfully improve cognitive function even years after brain injury, with more sessions producing better results. The safety record was excellent.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This was a small, non-randomized observational study with no control group; the absence of a sham condition means placebo effects cannot be ruled out.

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Study Details

Study Type Study
Category Neurological
Source Pubmed
PubMed ID 30950414
Year Published 2019
Journal Med Gas Res
MeSH Terms Adult; Brain Injuries, Traumatic; Female; Humans; Hyperbaric Oxygenation; Male; Mental Status and Dementia Tests; Military Personnel; Outcome Assessment, Health Care; Post-Concussion Syndrome; Rehabilitation Research; Severity of Illness Index; Stress Disorders, Post-Traumatic; Young Adult

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.