Clinical Study European neurology 1977

The use of hyperbaric oxygenation in the treatment of spinal cord lesions.

Holbach KH, Wassmann H, Linke D — European neurology, 1977

View Original on PubMed PMID 615712

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated the effects of hyperbaric oxygen therapy on 13 patients with persistent neurological deficits following compressive spinal cord lesions, monitoring neurological status, electromyography, and oxygen levels in blood and CSF.

What They Found

Six of 13 patients (46%) experienced marked improvement, especially in motor functions, while the remaining patients showed little change. Concurrent measurements in 8 patients revealed a considerable increase in both arterial and cerebrospinal fluid oxygen partial pressure during hyperbaric oxygen sessions.

Canadian Relevance

This study has no direct Canadian connection as it was conducted in Europe and does not involve Canadian researchers or patients.

Study Limitations

This study was limited by its small sample size of 13 patients and the absence of a control group for comparison.

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Study Details

Study Type	Clinical Study
Category	Neurological
Source	Pubmed
PubMed ID	615712
Year Published	1977
Journal	European neurology
MeSH Terms	Adolescent; Adult; Electromyography; Follow-Up Studies; Humans; Hyperbaric Oxygenation; Hypoxia; Ischemia; Male; Middle Aged; Neurologic Examination; Paralysis; Partial Pressure; Spinal Cord; Spinal Cord Compression

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Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology