RCT Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 2014

Therapeutic use of hyperbaric oxygen therapy for children with autism spectrum disorder.

Halepoto DM, Al-Ayadhi LY, Salam AA — Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2014

View Original on PubMed PMID 25052976

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reviewed existing publications on the physiological and clinical effects of hyperbaric oxygen therapy (HBOT) for children with autism spectrum disorder (ASD).

What They Found

The review indicated that several case series and randomised trials proposed that low pressure/low oxygen concentration hyperbaric treatment could improve the clinical manifestations of autism. While ASD affects as many as 1 in 91 children in the USA, specific numerical improvements from HBOT were not detailed in this review.

Canadian Relevance

This study has no direct Canadian connection as it reviewed international publications and did not involve Canadian researchers or participants.

Study Limitations

A key limitation is that the review is based on a limited number of reported studies regarding the effectiveness of hyperbaric oxygen therapy for autism spectrum disorder.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	RCT
Category	Neurological
Source	Pubmed
PubMed ID	25052976
Year Published	2014
Journal	Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
MeSH Terms	Autism Spectrum Disorder; Humans; Hyperbaric Oxygenation; Randomized Controlled Trials as Topic; Treatment Outcome

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Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology