Treatment of post-anesthesia dementia with perispinal etanercept injection and hyperbaric oxygen therapy: a case report. | Canada Hyperbarics Skip to main content
Case Study Journal of medical case reports 2017

Treatment of post-anesthesia dementia with perispinal etanercept injection and hyperbaric oxygen therapy: a case report.

Best S, Pavel DG — Journal of medical case reports, 2017

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported on a 77-year-old man with post-anesthesia dementia who was treated with hyperbaric oxygen therapy and perispinal etanercept injections.

What They Found

The 77-year-old patient, who had suffered from post-anesthesia dementia for 4.5 years, showed progressive improvements after receiving 40 sessions of hyperbaric oxygen therapy followed by 25 mg perispinal etanercept injections weekly for 5 months. By the 5-month follow-up, his cognitive and physical function were substantially restored, and a follow-up scan showed increased brain perfusion.

Canadian Relevance

This study has no direct Canadian connection as it was conducted outside of Canada.

Study Limitations

The primary limitation of this study is its design as a single case report, which prevents generalization of these findings to a broader patient population.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Case Study
Category Neurological
Source Pubmed
PubMed ID 28407792
Year Published 2017
Journal Journal of medical case reports
MeSH Terms Aged; Anesthesia; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Knee; Combined Modality Therapy; Dementia; Etanercept; Follow-Up Studies; Humans; Hyperbaric Oxygenation; Injections, Spinal; Male; Postoperative Complications; Recovery of Function; Tomography, Emission-Computed, Single-Photon

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology