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Review Diving Hyperb Med 2014

Unestablished indications for hyperbaric oxygen therapy

Mitchell S, Bennett M — Diving Hyperb Med, 2014

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reviewed existing evidence on the systematic clinical use of hyperbaric oxygen therapy (HBOT) for unestablished indications, particularly chronic brain injury, by examining multiple randomised, blinded, sham-controlled trials.

What They Found

The review found that multiple randomised, blinded, sham-controlled trials for hyperbaric oxygen therapy (HBOT) in conditions like cerebral palsy and mild traumatic brain injury showed no benefit compared to sham control. However, both HBOT and sham groups often improved, indicating a significant placebo or participation effect influenced outcomes in these studies.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

As a review, this study's findings are dependent on the quality and completeness of the existing trials it analyzed.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Review
Category Neurological
Source Pubmed
PubMed ID 25596836
Year Published 2014
Journal Diving Hyperb Med
MeSH Terms Adult; Brain Injuries; Cerebral Palsy; Child; Humans; Hyperbaric Oxygenation; Off-Label Use

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology