Usefulness of N-terminal pro-B-type natriuretic peptide (NT-ProBNP) as a marker for cardiotoxicity and comparison with echocardiography in paediatric carbon monoxide poisoning | Canada Hyperbarics Skip to main content
Study Cardiol Young 2020

Usefulness of N-terminal pro-B-type natriuretic peptide (NT-ProBNP) as a marker for cardiotoxicity and comparison with echocardiography in paediatric carbon monoxide poisoning

Turan C, Dogan E, Yurtseven A, Saz E — Cardiol Young, 2020

View Original on PubMed PMID 32571446
Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated if a blood test called NT-proBNP could effectively detect heart damage in children suffering from carbon monoxide poisoning, comparing its accuracy to echocardiography.

What They Found

The study included 69 patients and 60 healthy controls. They found that an NT-proBNP level above 480 pg/ml was 100% sensitive and 96% specific for identifying decreased heart function, a key sign of carbon monoxide-induced heart injury. There was a strong negative link between NT-proBNP levels and heart function (r = -0.769) and a positive link with carbon monoxide levels (r = 0.583).

Canadian Relevance

Covers a Health Canada-recognised indication (carbon monoxide poisoning).

Study Limitations

This study was conducted at a single paediatric emergency department, which may limit how broadly its findings apply to other populations.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

Was this summary helpful?

Study Details

Study Type Study
Category Neurological
Source Pubmed
PubMed ID 32571446
Year Published 2020
Journal Cardiol Young
MeSH Terms Biomarkers; Carbon Monoxide Poisoning; Cardiotoxicity; Child; Echocardiography; Humans; Male; Natriuretic Peptide, Brain; Peptide Fragments; Prospective Studies; Stroke Volume; Ventricular Dysfunction, Left; Ventricular Function, Left

Cite This Study

Share

Related Research

PLoS ONE | 2013 RCT

Hyperbaric oxygen induces late neuroplasticity in post stroke patients--randomized, prospective trial.

Efrati S, Fishlev G, Bechor Y, et al.
J Neurotrauma | 2018 Systematic Review

Hyperbaric oxygen therapy in the treatment of acute severe traumatic brain injury: a systematic review

Daly S, Thorpe M, Rockswold S, et al.
J Neurotrauma | 2012 Pilot Study

A phase I study of low-pressure hyperbaric oxygen therapy for blast-induced post-concussion syndrome and PTSD

Harch PG, Andrews SR, Fogarty EF, et al.
Scientific Reports | 2022 RCT

Hyperbaric oxygen therapy improves neurocognitive functions and symptoms of post-COVID condition: randomized controlled trial.

Hadanny A, Zilberman-Itskovich S, Catalogna M, et al.
PLoS ONE | 2013 RCT

Hyperbaric oxygen therapy can improve post concussion syndrome years after mild traumatic brain injury — randomized prospective trial

Boussi-Gross R, Golan H, Fishlev G, et al.
See all Neurological research
View on PubMed Back to Research Library
Discuss with a qualified healthcare professional. Then: Review Coverage Guide View Recognised Conditions

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 17, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology